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therefore, it cannot be ruled out that the effects of chc-1 RNAi on lifespan may be due to general sickness

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Therefore, limiting Asn metabolism in tumor cells and immunosuppressive cells in the TME and protecting and promoting Asn metabolism in anti-tumor immune cells should be a problem to be solved

Also good to consider: This study was funded by the company who created bremelanotide and a pharmaceutical company who licensed it