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270 Moreover, advancements in molecular biology have identified key growth factors and cytokines involved in tissue repair, such as transforming growth factor-beta (TGF-) and insulin-like growth factor-1 (IGF-1)

International Journal of Molecular Sciences , 21 (22)

[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee J-H, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL

PGC-1 also regulates the process of mitochondrial biogenesis [137, 138]

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Its important to understand that, because L-arginine is conditionally essential and supplementation has been shown to benefit only certain populations, most people do not need to supplement with L-arginine