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Various approaches such as bioconjugation with antibodies, protein and DNA [59], electrostatic interaction via citrate capping [60], covalent attachment via thiolation [61], and polymeric coating using chitosan or PEG [62] can be followed

Combination of BSO, cisplatin and TMZ: a high synergistic effect in vivo Finally, the synergistic effect of the combination of the three drugs that was observed in vitro was tested in vivo

J Clin Oncol 17 (2): 445-55, 1999

doi: 10.1016/j.tvjl.2017.04.010

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It is critical that compounders understand that quality should be built into the drug production, and that testing alone should not be relied on to ensure drug quality