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In phase 2 trials, cagrilintide alone produced dose-dependent reductions in body weight, with participants on the highest dose (4.5 mg weekly) losing roughly 10-15% of body weight over 26 weeks

However, over-supplementation may cause headaches, anxiety, or sleep issues in sensitive individuals

"That's why this discussion is so important and why the FDA's authority here is an important one to exercise appropriately with optimal outside advice," he says.

Preferred subcutaneous sites include the abdomen and the outer upper arms, providing straightforward access for individuals administering their own injections: Abdomen: Injections are given at least two inches away from the navel, allowing for a broad area of fat tissue

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