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Mediation of metabolism CYP19A1 In a Perturb-Seq screen of human GBM cells treated with radiotherapy, CYP19A1 , which encodes aromatase (CYP19A1), was found to be among the most differentially expressed genes over normal conditions
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Microb Cell Fact 22:102
It seems that expression of MT is sensitively and strictly regulated by the oxidative state induced in mitochondrial respiration
Interestingly, two samples (M12 and M14) induced ROS production but also increased CAT activity, possibly due to the presence of excess H 2 O 2 in the H4IIE- luc cells
This article walks through the science, typical timelines, safety issues, and practical next steps so you can decide what makes sense for you
