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Curcumin and its derivatives are typically characterized by poor solubility and structural instability, which significantly contribute to their low bioavailability
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doi:10.1160/th16-04-0320 Majeed H, Rodger M, Forgie M, et al
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Diverse stress signals produced during tumor initiation, such as those emitted by telomere attrition, DNA damage, nutrient deprivation, hypoxia, oxidative stress, and hyperproliferation, etc , can activate p53 and initiate the p53-dependent tumor suppression responses such as DNA repair, cell-cycle inhibition, senescence, autophagy, apoptosis [59]
Changes in plasma glucose, FFA, insulin and glycerol level Table 2 shows the changes in plasma glucose, FFA, insulin and glycerol levels
