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Purpose: A small crossover trial has suggested the efficacy of botulinum toxin (BoNT), but the long-term benefits are unknown

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J Clin Invest 2010;120:1774-85

X-ray crystallographic studies have demonstrated that copper coordination occurs through the N-terminal amino group of glycine, the deprotonated peptide nitrogen of the Gly-His bond, and the imidazole nitrogen of histidine, forming a square-planar geometry characteristic of Cu(II) complexes

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Patient Type Analysis The anti-obesity drugs market is predominantly driven by adult patients contributing 95.3% share in 2024, reflecting the high prevalence of obesity in this demographic