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Compared to exogenous recombinant GH (somatropin), Tesamorelin preserves the physiological pulsatility of endogenous secretion, maintaining better tissue response, avoiding GH-R desensitization, and presenting a more balanced metabolic profile (glycemic neutrality vs diabetogenic effect often documented with high-dose exogenous GH)

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Total intracellular glutathione contents and protein titration were then assessed as previously described 61

Wang, H., Guo, X., Zhou, J., Li, Y., Duan, L., Si, X., Zhang, L., Liu, X., Wang, M., & Shi, J

Variance components for fixed factors were estimated using restricted maximum likelihood (REML) method

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