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This elevated activity appears to be driven by a high turnover number

The multidrug efflux regulator AcrR of escherichia coli responds to exogenous and endogenous ligands to regulate efflux and detoxification

S., Cao, H., Hall, A

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They may also indirectly exert their antioxidant activity by stimulating endogenous antioxidant defense systems (e.g., glutathione peroxidase and superoxide dismutase) and/or inhibiting enzymes that generate large amounts of ROS, such as xanthine oxidase and NAD(P)H oxidase