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If supplementation is indeed required, it must be preceded by a careful consideration of the patients Se baseline status, gender, weight and so on ( 3.3 Dual role of Se deficiency in cretinism Cretinism often occurs in areas where endemic goiter is prevalent, with mucinous edema cretinism being the main manifestation of hypothyroidism without goiter

PMID 19447654

Clinical Chemistry 2009

03 Symptoms & signs: How can a deficiency be identified

In the genes coding for these enzymes, several single nucleotide polymorphisms have been described

illuminats that CAT, GPX, MnSOD, and glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) gene polymorphisms are not associated with the risk of chronic myeloid leukemia (CML) except GSTP1 depending on its strong restoring ability (Kogawa et al., 2021)