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The two latest meta-analyses do not prove the hypothesis that acetyl-l-carnitine exerts a positive effect on chemotherapy-induced polyneuropathy [69, 77], and its use is not recommended by the ASCO guidelines [76]

In a nitroglycerin-induced migraine rat model, sodium valproate demonstrated protective effects on mitochondrial energy metabolism and biosynthesis (71)

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ALCAR may also help promote normal glucose metabolism, making it a beneficial option for both performance horses and those requiring added support for metabolic health

Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation