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In the long-term toxicity experiment, continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose, providing a safety basis for its further research and application

The reason is that these antidepressants act as serotonin reabsorption inhibitors preventing serotonin from being rendered ineffective by the body

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Sterile 0.9% saline is appropriate where a physiological salt concentration is required by the experimental design