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While topical copper peptide serums have dominated the skincare market for years, injectable protocols are gaining traction in research communities for their systemic effects and potentially superior bioavailability

In the countries of origin, fresh leaves are consumed as a salad, as part of curry spice mixes, or cooked as a vegetable [226]

The 12 mg arm averaged 28.3% weight loss at 80 weeks

89 A placebo-controlled trial included 20 hypogonadal men who were on hemodialysis for kidney failure and had low-normal zinc levels

DOI: Published online: July 24, 2025 1 Institute of Medical Research, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea Correspondence to Seok-Woo Hong, PhD Institute of Medical Research, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Korea Email: [email protected] Won-Young Lee, MD Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Korea Email: [email protected] *Jinmi Lee and Eun-Jung Rhee contributed equally to this work as co-first authors

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