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L-Carnitine is a naturally occurring compound made from the amino acids lysine and methionine

A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor

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Rats treated with an oral dose of 600 mg/kg L-carnitine after artery occlusion had significantly reduced escape latency in the Morris water maze when tested 28 days after surgery, but no improvement in motor performance compared to vehicle treated rats

In this case, the mechanism of down-regulation is linked to promoter methylation (Scalise et al., 2012

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