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As a guide to treatment of acute ingestion, the acetaminophen level can be plotted against time since oral ingestion on a nomogram (Rumack-Matthew)
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Non- compartmental pharmacokinetic parameters were calculated from serum drug concentration- time profiles by use of WinNonlin software (Pharsight, Mountain View, CA, USA)

W.CarpenterJ.D'HaeseP

Synaptic density in carriers of C9orf72 mutations: a [ 11 C]UCB-J PET study

Additionally, some of the participants actually experienced a worsening of the Parkinsons symptoms that were then alleviated upon stopping the NAC supplementation
