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(5) Adverse effects and management: Cholinergic muscarinic effects such as diarrhea, abdominal cramping, and increased salivation are common and may be managed with agents such as propantheline or loperamide

Not only linear peptides but macrocyclic peptides can be produced through biological methods, with libraries generated using various techniques: disulfide bridge formation: cysteine residues can be randomly incorporated into sequences displayed on the surface of a phage, allowing the formation of disulfide bridges