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Other potential causes include: Gynecomastia may respond to initial medical treatments such as the switch-up of medications, diet and exercise, or the adequate treatment of contributing medical conditions

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Enkephalinergic, ghrelinergic, neurotensin and neuropeptide Y modulate cholinergic, dopaminergic, GABAergic, glutamatergic and serotonergic systems within the mesocorticolimbic neurocircuit

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Concurrent ionic concentration shifts generate the driving force for glutamate efflux, resulting in excessive synaptic glutamate accumulation [22]