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[95] ALW peptide exhibits isotype-dependent binding to anti-DNA antibodies in a sequence-specific manner

Phase 2 trial (NEJM, 2023) The landmark Phase 2 trial, published in the New England Journal of Medicine, randomized 338 adults with obesity to receive weekly subcutaneous retatrutide at doses of 1 mg, 4 mg, 8 mg, or 12 mg, or placebo, for 48 weeks

Data Availability Statement The data presented in this study are available on request from the corresponding author.

Month 2: Side effects usually ease, appetite reduction stabilizes, and headaches or lingering GI symptoms may appear occasionally

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Trauma to the Chest Wall A direct blow to the chest, such as a fall or car accident can sometimes lead to inflammation of the cartilage in the rib cage, resulting in costochondritis