melanotic macule of labia Mystery behind labial and oral macules: Clinical, dermoscopic and pathological aspects Laugier-Hunziker syndrome Dermatoscopic image of genital melanotic

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(Peck 2021) Metabolism : Phenytoin is metabolized in the liver via CYP 2C9 (~90%) and, to a lesser extent, 2C19 (~10%)

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This lesion characteristically is not associated with the nesting phenomenon of the nevus cells, and there are elongated retia, melanophages, and sparse dermal chronic inflammatory infiltrate

Acth receptor (Mc2r) specificity: what do we know about underlying molecular mechanisms