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By contrast, the inhibition of the de novo synthesis of GSH, by deleting either the catalytic (Gclc) or the modifier (Gclm) subunit of glutamatecysteine ligase (Gcl), dampens intracellular GSH, increases ROS, and impact T cell differentiation
Glutathione is often referred to as the bodys master antioxidant because it plays a central role in helping the body respond to oxidative stress, maintain cellular balance, and support normal detoxification processes
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