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Cells were imaged under GFP fluorescence to semi-quantitatively assess ROS levels

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Genes related to -glucoronidases have been shown to be enriched in an obesity-associated microbiome (35), and it has been hypothesized that increased -glucoronidase activity and increased enterohepatic cycling of toxins may play a role in the pathophysiology of obesity or diabetes (12)

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Currently, the PROTECT-ME study (ACTRN12617001515381), a triple-blind, randomized, parallel group, placebo-controlled trial, is trying to determine whether antenatal maternal melatonin supplementation improves neurodevelopmental outcomes at 2 years of age in children affected by FGR