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The ThT kinetic curve is characterized by a lag time ( t lag , the time in which ThT fluorescence reaches 5% of its maximum), dominated by the formation of oligomeric species not detectable by ThT, followed by an elongation phase, in which pre-fibrillar structures elongate to fiber, normally characterized by a time to half ( t 1/2 , the time in which the ThT fluorescence reaches half of its maximum value) and, finally, a plateau region in which the equilibrium is reached and the ThT fluorescence reaches its maximum value I max (Figure S1 in the Supporting Information)

Such information is valuable to public health as it would provide mechanistic evidence on curcumin as an adjuvant therapy for breast cancer

Our focus on bioavailability at Cymbiotika is rooted in the belief that supplements should work with your biology, not against it

Methods: A retrospective observational study was carried out in Lithuanian University of Health Sciences hospital - the largest teaching facility of tertiary care in country

The use of drugs targeting glutamate receptors and/or transporters in combination with approved therapies could offer a more specific scheme of treatment with fewer adverse effects

et al., 2022a)