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Description

Final Results of Phase I/II Study of Selinexor (SEL) with Sorafenib in Patients (pts) with Relapsed and/or Refractory (R/R) FLT3 Mutated Acute Myeloid Leukemia (AML)

Clusters 2, 4, and 5 were identified as profibrotic lipid-associated macrophages (LAMs) because of high expression of profibrotic genes (Fn1, Spp1, CD44) and lipid metabolism genes (Lpl, Trem2, Fabp4, Fabp5)

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NOTE: Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit

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