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Activated Caspase-1 then cleaves Gasdermin D (GSDMD), releasing its N-terminal pore-forming region (GSDMD-N) to form membrane pores, and simultaneously processes pro-IL-1 and pro-IL-18 into their mature, active forms (41)

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In total, 700 L of methanol (SCRC, Shanghai, China) was added to the lower chamber of a new 24-well plate, and the cleaned transwell chambers were placed into the plate and fixed for 30 min

26 Consistent with an oxidative stress-related etiology of cataract, there was also a diminished risk of cataract in male physician smokers who used multivitamins