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These are consistent with the class of compounds it belongs to and often lessen over time
Song TY, Chen CL, Liao JW et al (2010) Ergothioneine protects against neuronal injury induced by cisplatin both in vitro and in vivo
Ma Y, Chapman J, Levine M

These are called circumventricular organs (CVOs)

Furthermore, several small-molecule inhibitors targeting ferroptosis have demonstrated promising anti-fibrotic effects in animal models, yet their tissue-specificity, safety profiles, and clinical feasibility warrant further investigation
