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With this method, the authors revealed the role of SUMOylation in promyelocytic leukemia nuclear bodies (PML NBs) in early promyelocytic leukemia (PML) and discovered 59 SUMO-dependent PML-interacting proteins

10.1126/sciadv.abm1511 51 HiranoT.TagaT.NakanoN.YasukawaK.KashiwamuraS.ShimizuK.et al (1985)

Responsible prescribing means proper patient selection, evidence-informed dosing, baseline and follow-up lab monitoring where appropriate, documented informed consent, and clinical follow-up to assess response

visible artifice in week two means the dose was wrong.

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This project was funded in part by the FFG and the European Union (EFRE) under grant 912192