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Consult a qualified clinician before beginning any peptide protocol

PMA treatment of THP-1 cells causes the rearrangement of macrophage-specific kinome that leads to the activation of pro-inflammatory genes, such as IL-1, IL-8 and TNF-, making these cells biased toward a more pro-inflammatory phenotype (Richter et al., 2016)

Small molecule inhibitors ML385 and CPUY192018 are the two compounds that have been discovered recently (Lu et al., 2016)

Medical professionals cannot legally administer or recommend it

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Rihn, J., Smith, H., Vaccaro A.R..: Thoracolumbar Trauma