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Indeed, the PDH complex, which decarboxylates glycolytically derived pyruvate to acetyl coenzyme A and links cytoplasmic glycolysis to the mitochondrial tricarboxylic acid (TCA) cycle, is modulated by reversible phosphorylation by PDH kinase (PDK)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Glascock J., Sampson J., Connolly A.M., Darras B.T., Day J.W., Finkel R., Howell R.R., Klinger K.W., Kuntz N., Prior T., et al