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CORRESPONDING AUTHOR: Olivia Avidan MD Department of Internal Medicine Warren Alpert Medical School of Brown University Rhode Island Hospital Providence, RI 02903 Email: [email protected]

Tri B injections work through complementary mechanisms: B1 (thiamine) acts as a coenzyme in energy metabolism, B6 (pyridoxine) facilitates neurotransmitter synthesis (GABA, serotonin), and B12 (cobalamin) supports myelin formation and nerve conduction

Glutathione supplementation has demonstrated beneficial effects on gut health by reducing oxidative stress, improving gut microbiota composition, and supporting overall digestive function

When comparing NAD, Glutathione, and Nutrient IV therapy, its important to consider the specific health concerns and goals of the patient

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation