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It really is a vicious cycle but addressing depletions, including those in B12, can be a game-changer

No statistically significant mean differences in behavior tests or in glutathione status were identified between active and placebo groups. However, detailed data analysis suggests that methyl B12 may alleviate symptoms of autism in a subgroup of children

[Google Scholar] 221.Bodles AM, Banga A, Rasouli N, Ono F, Kern PA, Owens RJ

After that, I recommend once every two weeks for 2-3 months, followed by monthly injections until their condition normalizes

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