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Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

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TIGAR is a double phosphatase with two conserved pockets that bind phosphate molecules on the substrate by dephosphorylation (Geng et al., 2018)

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Since curcumin is lipophilic and readily crosses membranes, it may also chelate more metal ions intracellularly

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