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CFZ is highly lipophilic and is characterized by an unusually long pharmacokinetic half-life of up to 70 days, which is associated with extensive accumulation of the drug in the body [110,111,112]

Obstet.Gynecol
doi: 10.1191/026921601673324846
Millington DS, Terada N, Chace DH, Chen YT, Ding JH, Kodo N et al

In women, progesterone and estrogen levels keep fluctuating throughout life due to menstruation, pregnancy, and menopause which also influence their fat storage and metabolism

Food Res Int