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This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access 169 -4,5-dihydro-1 H -imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model

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The trajectory continues gradually, with many users experiencing steady losses extending into months 612 and beyond

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In March, a warm rain fell for nearly three days in succession