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Nrf2 is a central transcription factor that activates cellular antioxidant genes via the Keap1Nrf2ARE signalling pathway ( Nrf2 , which restricts antioxidant gene transcription by sequestering Nrf2 in the cytoplasm and promoting its degradation ( Nrf2 , thereby enhancing endogenous antioxidant defences

CJC-1295 is relatively more sensitive to DPP-IV degradation in solution due to the absence of albumin binding

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Peptides play a crucial role in various biological functions and have been widely applied in drug development over the past decade [2]