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Description
Some superoxides are transported to the cytosol, where they are dismutated to H 2 O 2 by the cytosolic enzyme SOD1 [16]
Yasumatsu, Matsuzaki et al
Therefore, various mechanisms for the hypopigmentary effect of Glutathione and Vitamin C have been proposed, with inhibition of tyrosinase being the most important
Nat Immunol (2022) 23(2):30317
The TF-Fe 3+ complex then binds to transferrin receptor 1 (TFR1) at the plasma membrane and is internalized through endocytosis [17]
These mutations are characterized by more severe iron accumulation and earlier onset of disease than Type 1 HH.6 Mutations in HAMP, the gene encoding hepcidin, result in Type 2 HH, a form of juvenile hemochromatosis
