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Administration of MS-275, an HDAC inhibitor, also increases expression of mGlu2 receptors, supporting the role of epigenetic mechanisms in the regulation of mGlu2 receptors [30]

Various preclinical models have been created that are showing the impact of metabolism on brain function and in particular the role that impaired metabolism plays in the neurodegeneration processes

Acetylcarnitine and cellular stress response: roles in nutritional redox homeostasis and regulation of longevity genes

doi: 10.1196/annals.1320.016

Cells transfected with pEX-GFP-hLC3WT were selected with G418 for use as permanent clones of GFP-hLC3WT overexpression

90,91 These impairments increase the risk of falls and foot ulcers due to unnoticed injuries
