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Singh SV, Srivastava SK, Choi S, Lew KL, Antosiewicz J, et al

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The term originates in the pharmacology community, defined as the rate at which a drug can reach the targeted action site

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Traditional physical barriers primarily provide mechanical isolation without modulating the local uterine microenvironment

Notably, these microspheres were observed to be capable of automatic adjustment: they exhibited enhanced degradation in OA joints, and the loading of celecoxib significantly inhibited this degradation