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Thyroid hormone receptors in human cultured fibroblasts: evidence for cellular T4 transport and nuclear binding

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

Altered mitochondrial function leads to a reduction in energy production and an increase in reactive oxygen species, which negatively impacts all cellular functions such as calcium handling, anaplerosis, proteostasis, apoptosis, and autophagy [27,28,29]

C.TongJ

32 ClinicalTrials (2017)