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745 Similarly, inactivation of the IlaM and IlaN involved in the biosynthesis of 3-nitrotyrosine ( 385 ) from Streptomyces atratus with subsequent feeding with 3-halogenated tyrosines and 3,5-dinitrotyrosine enabled the preparative isolation of 16 analogs of ilamycin F ( 386a ) (Figure 93C)

however, the accumulation of polyubiquitination of uS10 in the absence of Ubp2 and Ubp3 seemed to inhibit the RQC activity (Fig

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