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Results Single-cell and spatial analyses identify collagen-mediated immunosuppression as a predominant feature of the meningioma microenvironment To characterize the immunobiology of meningiomas and to identify immune therapeutic targets, single-cell RNA-seq (scRNA-seq) datasets with adjacent dura samples 2,3 were analyzed
Dose-dependent effects: Safety concerns increase substantially at doses exceeding 5060 mcg/day
10.1016/j.bbrc.2004.06.119 Biochem
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Despite the identified role of the arginine biosynthesis pathway in persistence, the underlying molecular mechanisms remain unclear
