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Description
While these observations provide insight into potential mechanisms, their translation to human cardiovascular outcomes has not been fully established

(2009) showed that quercetin inhibited tumor growth by activation of p16INK4a induced by promoter demethylation in colorectal cancer cells

Liu Z, Bao H, Cai J, Han J, Zhou L

doi: 10.1016/j.est.2023.108597 284 ChakrabortyS

This is highly speculative because: Oral bioavailability differs between species Route of administration affects systemic exposure Species differences in peptide metabolism and clearance are unknown Current Practice Patterns Current practice patterns from unregulated sources typically involve: Subcutaneous injection: 0.25-0.5 mg once or twice daily, administered near injection sites for localized effects or abdominally for systemic distribution

JAMA 2021;325(14):140313
