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Metformin, through the induction of 5' AMP-activated protein kinase and subsequently insulin sensitivity, has been widely used as a therapeutic agent in various conditions, including type 2 diabetes mellitus, PCOS and gestational diabetes (Reference Rice, Elia and Jawad42)
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In contrast with the other members of SLC16 family, MCT9 is responsible for carnitine, but also creatine, transport presumably at the basolateral membrane of enterocytes (Figure 2 and Table 1)
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