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The recent discovery of pharmacological ABHD5 ligands that disrupt the interaction between ABHD5 and PLIN1 (48) demonstrate that the dissociation of ABHD5 is sufficient to stimulate adipocyte lipolysis and that these protein interactions can be targeted pharmacologically (34, 48, 49)

Whats more, conformational changes are also observed in the supporting helix of the palm subdomain

Singh N, Madhira V, Hu C, Olex AL, Bergquist T, Fitzgerald KC, et al

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Peptide sind chemische Verbindungen aus Aminosuren

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