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doi: 10.1186/s12885-023-11589-5 125 ZhangLHobeikaCSKhabibullinDYuDFilippakisHAlchoueiryMet al

Oxygen-derived species: Their relation to human disease and environmental stress

Brain Behav Immun 42:96108

For instance, a review we conducted at this time of ClinicalTrials.gov.org using NAD + as other term input and the following precursors as intervention reveals that there are 4 clinical trials investigating NA, 7 trials focused on NAM, 8 trials administering NAD + , 16 trials studying NMN, and over 60 trials exploring NR with NAD + measurements included as readout

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HMGB1-mediated macrophage inflammation requires the receptor for advanced glycation end products (101, 102)
