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Notably, the use of human THP-1 cells allowed us to evaluate also the contribution of NLRP3 inflammasome in treatment-induced responses, and this is of crucial importance given the inflammasome key role in immune reactions, its interaction with the complement pathway, and the fact that it can be activated by paclitaxel [8, 37, 38]

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When cell turnover slows with age or when dead cells build up on the surface, the complexion can look dull, regardless of pigment levels

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Most studies focus on short-term use 2

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