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While passive diffusion was initially proposed as the main absorption route, recent evidence indicates that specific transmembrane transporters including Na-taurocholate cotransporting polypeptide, organic anion-transporting polypeptides, L-type amino acid transporters, and monocarboxylate transporters also facilitate LT4 uptake

[DOI] [PubMed] [Google Scholar] 82.Yamashita K., Hitoi A., Taniguchi N., Yokosawa N., Tsukada Y., Kobata A

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In a study by Zhao et al., the primary follicles were triggered by IGF-1 through the measurement of DNA increase in follicular cells

In terms of metabolic changes, they mainly exhibited iron deposition, lipid peroxidation damage to the cell membrane, and decreased glutathione (GSH) content (Figure 1) (Meyer et al., 2021)

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