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2017 Feb Grant Tinsley, Rachael Ajmera

The development of 5-amino-1MQ also represents a broader proof-of-concept for targeting metabolic intersections as a research strategy

Freezethaw: Avoid repeated freezethaw cycles of the reconstituted solution

Dosages used in rodent studies range from 10mg/kg/day to 150mg/kg/day [1, 6, 11]

Does not significantly inhibit related SAM-dependent methyltransferases or enzymes in the NAD+ salvage pathway NAD+ increase : By preventing nicotinamide methylation to 1-MNA, more nicotinamide remains available for conversion to NMN and subsequently to NAD+ via the salvage pathway
