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A third type of crystal-induced arthritis, hydroxyapatite deposition disease , has a type of crystal that needs special studies (one such study is electron microscopy) for identification

Emerging evidence has revealed that GSK 3 phosphorylates various tumor factors (TFs), including cyclin D1, cyclin E, AP-1, c-Jun, p53, p65, Snail, c-Myc and -catenin, which would facilitate their degradation and prevent them from entering the nucleus

As such, there is no agreed recommended safe dosage, and some side effects might occur depending on individual response

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Among various biomaterials, thermosensitive hydrogels like PCLA-PEG-PCLA exemplify promising carriers that undergo sol-gel transition at body temperature, allowing in situ gelation and sustained exosome release for over seven days, thereby enhancing endometrial regeneration outcomes (Figure 3A)

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