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Description
Under periods of fasting, the liver facilitates breakdown of glycogen stores and secretion of TAG to supply peripheral tissues

*Osterholt, T., Gloistein, C., Todorova, P., Becker, I., Arenskrieger, K., Melka, R., Koehler, F

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Intracellular unesterified fatty acids must first undergo thio-esterification to coenzyme A, a process catalysed by acyl-CoA synthases and consuming the equivalent of two ATP, with formation of acyl-CoAs, i.e., to activate fatty acids
These findings were further confirmed by TMAO levels in urine samples (Figure S2a-b)

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