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A narrative review of glutathione supplementation reported that 37.5 percent of participants receiving 1.2 g of glutathione twice weekly for six weeks experienced temporary lightening, yet benefits faded within six months, and 32 percent experienced adverse events such as liver dysfunction or anaphylaxis

Sci Rep 10:11478

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Chao CT, Chen YC, Chiang CK, Huang JW, Fang CC, Chang CC, et al